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musseco stands for [Mu]lti-[S]tate [S]peciation and [E]xtinction [Co]alescent and is an R package to estimate parameters for a speciation and extinction coalescent process.

We have implemented the BiSSECo ([Bi]nary-[S]tate [S]peciation and [E]xtinction [Co]alescent) model in which we can estimate the within-host and between-host replicative fitness using a fixed time-scaled tree.

Installation

# You will need to install the R package devtools 
# (https://github.com/r-lib/devtools)

install.packages("devtools")
devtools::install_github("emvolz-phylodynamics/musseco")

Tutorials

  • We recommend that you read the Get started to understand the implementation of BiSSECo.

Author

musseco has been developed by Erik Volz

Additional information

musseco works on a fixed phylogenetic tree and therefore is not a program that will estimate the tree for you.